|
UDS (urine drug screen) |
Causing False Positive Substance |
Possible Treatment-Related |
References |
|
Amphetamine and 3,4-methylenedioxymethamphetamine
(MDMA) |
Amantadine Aripiprazole Bupropion chlorpromazine Esmolol Ephedrine Labetalol Dimethylamylamine (DMAA) Methylphenidate promethazine Selegiline Phentermine Pseudoephedrine Ranitidine Selegiline Trazadone |
trazodone |
[1] [2] [3] [4] [5] |
|
Benzodiazepine |
50% of Efavirenz user Oxaprozin Sertraline |
|
[3] [4] [5] |
|
Cannabinoid |
Efavirenz 600mg lumacaftor/ivacaftor Ibuprofen Naproxen |
|
[3] [4] [5] [6] |
|
Ketamine |
Quetiapine (Seroquel) |
|
[7] |
|
Methadone |
quetiapine |
|
[3] |
|
Opiate, Opioid |
Quetiapine 69.2% Levofloxacin, ofloxacin and
pefloxacin users Poppy seeds Verapamil |
Buprenorphine Naloxone |
[3] [4] [5] [7] |
|
Phencyclidine (Angel Dust) |
Tramadol Venlafaxine Medicon (Dextromethorphan) Diphenhydramine Ketamine |
|
[3] [4] [5] |
|
Tricyclic Antidepressants |
Carbamazepine Cyclobenzaprine Diphenhydramine Phenothiazines |
|
[5] |
1.
Caricasole V, Spagnolo G, Di
Bernardo I, Cirnigliaro G, Piccoli E, Dell'Osso B. Aripiprazole causing false
positive urine amphetamine drug screen in an adult patient with bipolar
disorder. Compr Psychiatry. 2019 Oct;94:152126. doi:
10.1016/j.comppsych.2019.152126. Epub 2019 Sep 5. PMID: 31518847.
2.
Adashek JJ, Khadilkar A, Enciso
J, Rane R, Wu R. A Case of Esmolol-Induced False-Positive Amphetamine Urine
Drug Test. Cureus. 2021 Jan 2;13(1):e12429. doi: 10.7759/cureus.12429. PMID:
33542876; PMCID: PMC7849827.
3.
Saitman A, Park HD, Fitzgerald
RL. False-positive interferences of common urine drug screen immunoassays: a
review. J Anal Toxicol. 2014 Sep;38(7):387-96. doi: 10.1093/jat/bku075. Epub
2014 Jul 1. PMID: 24986836.
4.
Shafiq Q, Mutgi A. Urine opiate
screening: false-positive result with levofloxacin. CMAJ. 2010 Oct
19;182(15):1644-5. doi: 10.1503/cmaj.091508. Epub 2010 Sep 27. PMID: 20876267;
PMCID: PMC2952012.
5.
Algren DA, Christian MR. Buyer
Beware: Pitfalls in Toxicology Laboratory Testing. Mo Med. 2015
May-Jun;112(3):206-10. PMID: 26168592; PMCID: PMC6170116.
6.
Kissner D, LeFlore Y, Narayan
SB, Marigowda G, Simard C, Le Camus C. False-positive cannabinoid screens in
adult cystic fibrosis patients treated with lumacaftor/ivacaftor. J Cyst
Fibros. 2018 Nov;17(6):e51-e53. doi: 10.1016/j.jcf.2018.08.006. Epub 2018 Sep
12. PMID: 30217546.
7.
Liu CH, Wang HY, Shen SH, Chiu
YW. False positive ketamine urine immunoassay screen result induced by
quetiapine: A case report. J Formos Med Assoc. 2017 Sep;116(9):720-722. doi:
10.1016/j.jfma.2017.04.008. Epub 2017 May 8. PMID: 28495417.
edited by Yu-Jang Su Sep 12, 2021.