Recent 10 Substances Causing Methemoglobinemia in Scientific Articles

 

Recent 10 substances causing Methemoglobinemia in scientific articles
Year	Month	Country	Substance	Antidote	reference
2024	Feb	Australia	Primaquine	methylene blue.	[1]
2024	Jan	USA	Dapsone	3% Methylene blue	[2]
2024	Jan	India	Phenazopyridine200 mg three times a day for 14 days	methylene blue and oxygen	[3]
2023	Oct	China	sodium nitrite	100 mg of methylene blue	[4]
2023	July	Haifa, Israel	Anesthetic Cream lidocaine 2.5% and prilocaine 2.5%, applying it excessively every few hours daily for 2 weeks.	intravenous methylene blue 72 mg (1 mg/kg)	[5]
2023	May	UK	Alkyl nitrites ('poppers')	Methylthioninium chloride	[6]
2023	Feb	China	Nitrobenzene	methylene blue	[7]
2022	Dec	USA	Nail Polish Remover isobutyl nitrite-containing	methylene blue at a rate of 1 mg/kg	[8]
2022	Nov	India	100 mL of a herbicide marketed as FIRE-007	methylene blue 50 mg in 100 mL NS was given over 10 min	[9].
2022	Sep	USA	Presumed ingestion of lava lamp contents	Three doses of  ascorbic acid 5 g	[10].

References

[1]. https://pubmed.ncbi.nlm.nih.gov/38336484/

[2]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847900/

[3]. https://pubmed.ncbi.nlm.nih.gov/38167589/

[4]. https://pubmed.ncbi.nlm.nih.gov/38028640/

[5]. https://pubmed.ncbi.nlm.nih.gov/37611308/

[6]. https://pubmed.ncbi.nlm.nih.gov/37247947/

[7]. https://pubmed.ncbi.nlm.nih.gov/36895721/

[8]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805361/

[9]. https://casereports.bmj.com/content/15/11/e253407.long

[10]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9603889/

Edited by Yu-Jang Su   Feb 15, 2024