|
Year |
Country |
Substance / Dose |
Treatment / Outcome |
Reference |
|
2003 |
Taiwan |
Oral application of ABM (20 mg/kg) |
Concomitant epinephrine injection [100
micro-gm/ kg, subcutaneously (s.c.). |
1 |
|
1999 |
Taiwan |
Eighteen patients with abamectin
(Agri-Mek; 2% wt/wt abamectin) exposure and 1 with ivermectin (Ivomec; 1%
wt/vol ivermectin) ingestion. |
Male: Female =14: 5 37% coma 37% admit to ICU 21% asymptomatic 16% hypotension 5% die of MOF. |
2 |
|
2022 |
Taiwan |
60 had ingested emamectin pesticides, and
4 had ingested abamectin. |
Drowsiness (47%) Shortness of breath (SOB)/dyspnea (33%) Nausea/vomiting (22%). (27%) were intubated. (31%) had severe outcomes. (78%) were admitted 42% required intensive care unit (ICU). 6.3% died GCS score < 13 (OR 68.1, 95% CI
3.8-999) and the presence of SOB/dyspnea (OR 50.2, 95% CI 3.0-849.9) were
associated with severe outcomes. |
3 |
|
2015 |
People's Republic of China |
Ingestion of a large dose of abamectin on
purpose |
Rapidly recovered consciousness after
administration of flumazenil. |
4 |
|
2004 |
Taiwan |
Proclaim insecticide (Syngenta, Taiwan),
consisting of 2.15% w/w emamectin benzoate in 2, 6-bis (1,
1-dimethylethyl)-4-methyl-phenol and 1-hexanol. |
Transient gastrointestinal upset with
endoscopy-proven gastric erosion and superficial gastritis, mild central
nervous system depression, and aspiration pneumonia. Treated successfully
with gastric lavage, administration of activated charcoal, and empiric
antibiotics.
|
5 |
|
2007 |
Turkey |
Toxic effects of abamectin are usually
seen after abamectin oral ingestions. |
Altered mental status, respiratory
failure, and hypotension. |
6 |
|
2016 |
China |
acute avermectins poisoning |
Nystagmus is rarely reported |
7 |
|
2014 |
Iran |
3600 mg abamectin orally. |
Gastric lavage charcoal was administered. Altered mental
status drowsiness, hypotension, tachycardia and dermal erythema. Treated as H1 and H2 blockers and
vasoactive agents Altered mental status could be considered
as the first sign of abamectin intoxication. Conservative treatment is
recommended. |
8 |
|
2020 |
People's Republic of China |
400 mL of 5% abamectin pesticide. |
Serious brain dysfunction and abnormal EEG caused by abamectin poisoning are treatable. Despite poor clinical and
EEG findings at the outset, recovery is still possible. |
9 |
1.
https://pubmed.ncbi.nlm.nih.gov/12948083/
2.
https://pubmed.ncbi.nlm.nih.gov/10381994/
3.
https://pubmed.ncbi.nlm.nih.gov/35916769/
4.
https://pubmed.ncbi.nlm.nih.gov/26360693/
5.
https://pubmed.ncbi.nlm.nih.gov/15462160/
6. https://pubmed.ncbi.nlm.nih.gov/17453886/
7. https://pubmed.ncbi.nlm.nih.gov/24280654/
8. https://pubmed.ncbi.nlm.nih.gov/25948975/
9. https://pubmed.ncbi.nlm.nih.gov/33094704/
Edited by Yu-Jang Su Aug 19, 2023
