Substance
Abrin [1]
Common name or Trade name, used in
Rosary
pea 雞母珠 Abrus precatorius
紅豆、鴛鴦豆、赤小豆、相思豆、相思子、相思藤、雞母真珠、雞母子、黑 頭小雞、土甘草、美人豆或紅珠木 [2]
jequirity bean，rosary pea，precatory bean，crab's-eye [3]
potential for use as a bioterrorism agent [4].
Involving system
GI system: fever, vomiting, diarrhea, and
dehydration [5]
Neurologic: central pontine myelinolysis [6]
Presentation
Haemorrhagic enterocolitis, bilateral septal
vein thrombosis, and basal ganglia haemorrhage [7]
Seizure, progressive encephalopathy and death [8]
death occurs from multi-organ failure [4].
Diarrhea
Antidote and Treatment
lack of antidote [4]
Gastric lavage, De-contamination
Gastric acid suppression by proton pump inhibitor (PPI)
liver protection, hemostasis,
blood volume and electrolytes resuscitation, continuous renal replacement
therapy (CRRT), and hemoperfusion (HP) [9].
Disposition
Depends on the patient’s situation.
References
[1] Goldfrank’s Toxicologic emergencies. 11th
ed. P.1608.
[2]. https://www.agriharvest.tw/archives/18354
[3] http://tcm-toxic.kmu.edu.tw/index.php/%E9%9B%9E%E6%AF%8D%E7%8F%A0
[4] https://pubmed.ncbi.nlm.nih.gov/32475191/
[5] https://pubmed.ncbi.nlm.nih.gov/25754813/
[6] https://pubmed.ncbi.nlm.nih.gov/29675076/
[7]. https://pubmed.ncbi.nlm.nih.gov/36061310/
[8] https://pubmed.ncbi.nlm.nih.gov/31456429/
[9] https://pubmed.ncbi.nlm.nih.gov/28682903/
