速展王 (離子型黏著劑)
SUBSTANCE: Polyetheretherketone, PEEK; poly-ether siloxane.
cyclic siloxanes D4 (tetramethylcyclotetrasiloxane)
and
D5 (decamethylcyclopentasiloxane) and The short-linear
HMDS (hexamethyldisiloxane)
General information: Seek medical advice.
If breathing is irregular or
stopped, administer artificial respiration.
Inhalation: Move to fresh air.
Skin Contact: Wash off immediately with soap and plenty of water.
Wash off immediately with plenty of water
for at least 15 minutes.
Eye contact: Rinse immediately with plenty
of water for at least 15 minutes. Rinse
immediately with plenty of water, also
under the eyelids, for at least
15 minutes. Remove contact lenses.
Ingestion: Prevent aspiration of vomit. Turn victim's head to the side.
Never give anything by mouth to an
unconscious person. If swallowed, seek
medical advice immediately and show this
container or label.
Personal Protection for First aid
Responders: Use personal protective equipment., Wear self-contained
breathing apparatus for firefighting if necessary.
Most important symptoms/effects, acute and
delayed
Symptoms: Up to now no symptoms are
known. Hazards: No data available.
Indication of immediate medical attention
and special treatment needed
Treatment: Treat symptomatically
Toxicokinetic: D4 is eliminated via the lungs and metabolised D4 via urine and
faeces
Acute toxicity
In general the acute toxicity of
siloxanes is considered low. LD50 following oral
administration of D4 in rats is reported to
be more than 4,500 mg/kg and
more that 5,000 mg/kg for HMDS. LC50
in rats exposed to D4 was >12.17
mg/l and >48 mg/l when exposed to HMDS
(European Commission 2000).
LD50 following dermal application of D4 was
>2400 mg/kg bw. Several studies with dermal application of HMDS have shown
greater LD50 values, but
mortality was observed at 10000 mg/kg bw.
Toxic effects at 10000 mg/kg included
gross pathological findings (lung, kidney, bladder, heart), while
clinical findings (altered activity, ataxia, gasping and eschar formation)
occurred in small numbers of rabbits.
Investigation of subacute oral toxicity in
rats administered between 25 and
1600 mg/kg per gavage over two week with
five applications per week caused
increased relative liver weights in
female animals at 100 mg/kg and male animals at 400
mg/kg. Absolute liver weight was also increased in female rats at
400 mg/kg. Decreased body weight was seen
at the highest concentration in
both male and female animals (BAuA 2001).
References:
https://www.palmerholland.com/Assets/User/Documents/Product/49053/8825/MITM11654.pdf
https://www2.mst.dk/udgiv/publications/2005/87-7614-756-8/pdf/87-7614-757-6.pdf
Edited by Yu-Jang Su Oct 19, 2023.
